The RNA World & Biological Control systems

The role of RNA in the life of a cell and how RNA is increasingly used as a tool to understand biology. RNA interference, CRISPR Genome Editing, non-coding RNAs, together with the latest work on well-known RNA based activities. These include transcription, RNA splicing, RNA stability, RNA export and translation and how all these processes are coupled in the cell to ensure efficient, quality-controlled gene expression. The latest innovations and discoveries in the RNA world and their application will be studied as they evolve. Dynamic systems and their control, modelling and block diagrams of Open and 25% closed loop systems, basic concept of feedback control systems, stability criteria, speed of response; Modelling the body as compartments, behaviour in simple compartmental system, pharmacokinetic model, multi compartmental system. Distribution and accessibility of body water & tissue compartments, basis for zero order & first order chemical kinetic behaviour in the biological system will be studied. Practical applications of stochastic models to tracer kinetics.