BME 445

Engineering model in Physiology

Build on a basic understanding of physiology (from pre-requisites) to develop a more in- depth level of understanding that will enable engineering analysis of selected physiological systems: (1) cardiovascular system, (2) pulmonary gas transport system, (3) neuro-muscular spinal reflex system, (4) cellular volume control system, and (5) action potential generating system in excitable cells. Be able to translate the understanding of physiological function into an engineering model based on block-diagram analysis of a dynamic system whose function is based on a differential equation. Develop skill in applying a high-level engineering tool for block diagram modeling (SIMULINK). Be able to apply engineering models of physiological systems to answer questions relevant to the design of biomedical engineering devices or processes. Be able to break down a complex physiological system into the function of its component subsystems, and then build an engineering model based on subsystems. Be able to apply basic principles of steady-state and dynamic negative feedback control to physiological systems. Be able to recognize the difference between the roles of variables and parameters in a model. Be able to use dimensionless values or principles of dimensional analysis to determine how 
parameters must vary with the scale of the individual being modeled. Be able to use inverse modeling to determine unknown parameters from known observations 
of model output variables.

Course Code
BME 445
Biomedical Engineering
Sumas University
400 Level, Undergraduate
Sumas University Lecturer
First Semester
2 Units