Clinical Chemistry III

Causes and laboratory investigation of disorders of iodine metabolism. Plasma proteins in health and disease. Definition, causes and investigation of paraproteinemia; Bence-Jones proteinuria and significance. Diseases of muscle. Lipidemias. Definition, causes and investigation of hyperlip-proteinaemia and hypoliproteinaemia. Causes and investigation of nutritional disorders. Definition, causes and investigation of diabetes mellitus, hypoglycemia. Types, causes and features of glycogen storage diseases. Definition and causes of hypernatraemia and hyponatraemia, hyperkalemia and hypokalemia. Investigation of water and electrolyte imbalance. Homeostasis and clinical chemistry. Acid-base balance. Biotechnology-recombinant DNA. Hybriodoma. Biochemistry of neoplastic disorders. Kidney diseases, aminoacidurias. Trace elements – bioavailability function, interaction. Toxicology. Diseases of the nervous system.