Antimicrobial Drug Evaluation

Properties of an ideal antimicrobial agent. Classification and examples of various classes of antimicrobial agents such as disinfectants, antiseptics, preservatives and antibiotics and chemotherapeutic agents. In vitro methods of evaluating Disinfectants, Antiseptics, Preservatives, Antibiotics including the phenol coefficient tests, Kelsey-Sykes and improved Kelsey-Sykes tests, Microbial Challenge Tests, MIC, MBC; evaluation of antimicrobial interactions. Principles and applications of antibiotic bioassay; culture and sensitivity test.